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Coronavirus: Some Clinical Trial Data | In the Pipeline
Here are 9 ways to stay safe. Drug Status Rx. New York State will start coronavirus drug trials Tuesday in an attempt to control the pandemic's impact on the state, said New York Gov. Andrew Cuomo.
New York is the hardest-hit state in the U. During a news conference on Sunday, Cuomo announced that the state has acquired 70, doses of hydroxychloroquine, 10, doses of zithromax and , doses of chloroquine.
The trials will start Tuesday, he said. Hydroxychloroquine and chloroquine are antimalarial drugs. The cleaning agent has the same active ingredient as the medicine chloroquine but is formulated differently. Chloroquine has been used to treat malaria since the s.
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Hydroxychloroquine came along a decade later and has fewer side effects. The latter is sold in generic form and under the brand name Plaquenil for use against several diseases. The drugs can cause heart rhythm problems, severely low blood pressure and muscle or nerve damage. Plaquenil's label warns of possible damage to the retina, especially when used at higher doses, for longer times and with certain other medicines such as the breast cancer drug tamoxifen.
Hydroxychloroquine is far safer, but its side effects are still significant," Meghan May, a microbiologist at the University of New England College of Osteopathic Medicine in Biddeford, Maine, wrote in an email. That's where the evidence comes in — and, so far, there is not much.
When disaster visits the vulnerable
Hydroxychloroquine curbed coronavirus' ability to enter cells in lab tests, researchers reported last week in the journal Nature Medicine. That doesn't mean it would do the same in people or that they could tolerate the doses tested in the lab.
A report from China claimed chloroquine helped more than patients at 10 hospitals, but they had various degrees of illness and were treated with various doses for different lengths of time. They also might have recovered without the drug — there was no comparison group.